Efficient In Situ Regeneration of NADH Mimics by an Artificial Metalloenzyme
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چکیده
منابع مشابه
Chiral alcohol production by NADH-dependent phenylacetaldehyde reductase coupled with in situ regeneration of NADH.
Phenylacetaldehyde reductase (PAR) produced by styrene-assimilating Corynebacterium strain ST-10 was used to synthesize chiral alcohols. This enzyme with a broad substrate range reduced various prochiral aromatic ketones and beta-ketoesters to yield optically active secondary alcohols with an enantiomeric purity of more than 98% enantiomeric excess (e.e.). The Escherichia coli recombinant cells...
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ژورنال
عنوان ژورنال: ACS Catalysis
سال: 2016
ISSN: 2155-5435,2155-5435
DOI: 10.1021/acscatal.6b00258